Clinical Comparison of 5% Potassium Nitrate and 10% Strontium Chloride Toothpastes in Alleviating Dentin Hypersensitivity Following Manual Scaling: A Pilot Study (2025)

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Efficacy of a Toothpaste Containing 5% Potassium Nitrate in Desensitizing Dentin Hypersensitivity

Anton Rahardjo

Asian Journal of Pharmaceutical and Clinical Research, 2016

Objective: This clinical trial compared the pain reduction achieved by a 5% potassium nitrate (KNO ) desensitizing toothpaste paste versus placebo on adult patients with tooth hypersensitivity. 3 Methods: Investigators identified adult patients with hypersensitive teeth (which are nonpathologic such as caries) after scaling. Each hypersensitive tooth was isolated and tested with a blast of compressed cold air delivered from a three-in-one syringe. The patient was then asked to indicate a sensitivity score using the visual analog scale (VAS) from 0 to 10. Patients received 30 seconds application of desensitizing toothpaste containing 5% potassium nitrate (KNO ) (Group 1) and the others with placebo toothpaste (Group 2). The teeth were tested for the second time with compressed cold air, and the patients were asked to report the VAS again. A non-parametric test was used to analyze the results following a normality test of the VAS. 3 Results: The Primary sampling unit for analysis were...

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The efficacy of strontium and potassium toothpastes in treating dentine hypersensitivity: a systematic review

david gillam

International journal of dentistry, 2013

Objectives. The aim of the present paper was to review the published literature in order to identify all relevant studies for inclusion and to determine whether there was any evidence of the efficacy of strontium and potassium toothpastes in the treatment of dentine hypersensitivity (DH). Methods. Following a review of 94 relevant papers both from searching electronic databases (PUBMED) and hand searching of relevant written journals, 13 studies were identified, and 7 papers (1 for strontium-based toothpastes and 6 for potassium-based toothpastes) were finally accepted for inclusion. The main outcome measures were the methodology and assessment used by Investigators in studies designed to evaluate DH. Results. The results of the present paper would indicate that the reported efficacy of both strontium- and potassium-based toothpastes in relieving DH is questionable. Conclusions. The results from the present paper would appear to support the conclusions of previous investigators that...

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Evaluation of the clinical efficacy of potassium nitrate desensitizing mouthwash and a toothpaste in the treatment of dentinal hypersensitivity

Neetha Shetty

Journal of clinical and experimental dentistry, 2012

Potassium Nitrate has been used as a desensitizing agent to treat dentinal hypersensitivity. The effectiveness of a potassium nitrate is evaluated both in the form of a toothpaste and a mouthwash in a clinical study. Thirty patients were assessed using evaporative stimuli and thermal stimuli and response was evaluated using Visual Analogue Scale at baseline, at 2 weeks and 4 weeks. The patients were divided into. group I: fifteen patients who used toothpaste containing 5% potassium nitrate, sodium fluoride, xylitol and triclosan, group II: Fifteen patients who used mouthwash containing 3% potassium nitrate, sodium fluoride, xylitol and triclosan . The results of both the assessment methods indicated that potassium nitrate toothpaste as well as mouthwash showed statistically significant decrease in the sensitivity score on a Visual Analogue Scale. This was effective in reducing the symptoms of dentinal hypersensitivity when used either as toothpaste or as a mouthwash. But, there were...

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Efficacy of a 3% Potassium Nitrate Desensitizing Mouthwash in the Treatment of Dentinal Hypersensitivity

Dr.Vijay chava

Journal of Periodontology, 2001

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Comparing the efficacy in reducing dentin hypersensitivity of a new toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride to a commercial sensitive toothpaste containing 2% potassium ion: an eight-week clinical study on Canadian adults

Diane Cummins

The Journal of clinical dentistry, 2009

This paper presents the results of one of two eight-week dentin hypersensitivity clinical studies in which the efficacy of a novel toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride as sodium monofluorophosphate (MFP) was compared to that of a benchmark commercial toothpaste containing 2% potassium ion, dosed as 3.75% potassium chloride, and 1450 ppm fluoride as sodium fluoride (NaF). An eight-week clinical study, with seventy-seven patients, was conducted in Mississauga, Canada using a double-blind, stratified, two-treatment design. Tactile sensitivity assessments, as well as air blast sensitivity assessments, were used to compare the efficacy of the two products. This clinical study demonstrated that the new toothpaste, containing 8.0% arginine and 1450 ppm MFP in a calcium carbonate base, provided a significant reduction in dentin hypersensitivity when used over a period of eight weeks. The study also showed that this new arginine toothpaste provided si...

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Comparing the efficacy in reducing dentin hypersensitivity of a new toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride to a commercial sensitive toothpaste containing 2% potassium ion: an eight-week clinical study in Rome, Italy

Diane Cummins

The Journal of clinical dentistry, 2009

OBJECTIVE This paper presents the results of one of two eight-week dentin hypersensitivity clinical studies in which the efficacy of a novel toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride as sodium monofluorophosphate (MFP) was compared to that of a benchmark commercial toothpaste containing 2% potassium ion, dosed as 3.75% potassium chloride, and 1450 ppm fluoride as sodium fluoride (NaF). METHODS An eight-week clinical study, with eighty patients, was conducted in Rome, Italy using a double-blind, stratified, two-treatment design. Tactile sensitivity assessments, as well as air blast sensitivity assessments, were used to compare the efficacy of the two products. RESULTS This clinical study showed that the new toothpaste containing 8.0% arginine and 1450 ppm fluoride as MFP in a calcium carbonate base provided a significant reduction in dentin hypersensitivity when used over a period of eight weeks. The study also showed that this new arginine toothpa...

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Effects of potassium ions on dentine sensitivity in man

Orapin Ajcharanukul

Archives of Oral Biology, 2007

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Use of multiple sensitivity measurements and log it statistical analysis to assess the effectiveness of a potassium-citrate-containing dentifrice in reducing dentinal hypersensitivity

mark wolff

Journal of Clinical Periodontology, 1992

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Comparison of Vantej and Dente 91 Toothpastes in the Management of Dentin Hypersensitivity: A Randomised Clinical Trial

Priyanca Panigrahi

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH

Introduction: Dentinal hypersensitivity is a prevalent and distressing dental condition characterised by acute, transient pain or discomfort arising from exposed dentin in response to external stimuli, such as variations in temperature, mechanical stimuli, or consumption of acidic or sweet foods. Dentinal Hypersensitivity (DH) impacts daily activities, such as eating, drinking, and oral hygiene practices. Dentifrices are commonly used in the treatment of hypersensitivity, as they relieve sensitivity by obstructing nerve pathways through the formation of compounds. Aim: The aim of the study is to evaluate and compare the efficacy of two types of desensitising toothpastes, Vantej and Dente 91, in treating DH. Materials and Methods: A randomised controlled clinical trial was conducted with 40 patients who had a minimum of two hypersensitive teeth. The clinical investigation took place in a dental set-up in Bhubaneswar, Odisha, from July to August 2022. The patients were randomly alloca...

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Efficacy in reducing dentine hypersensitivity of a regimen using a toothpaste containing 8% arginine and calcium carbonate, a mouthwash containing 0.8% arginine, pyrophosphate and PVM/MA copolymer and a toothbrush compared to potassium and negative control regimens: An eight-week randomized clini...

Karol Ramirez

Journal of Dentistry, 2013

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Clinical Comparison of 5% Potassium Nitrate and 10% Strontium Chloride Toothpastes in Alleviating Dentin Hypersensitivity Following Manual Scaling: A Pilot Study (2025)

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